Evidence map›Paper›PMID 42894039›Full record

ArticleNeurosurgical review2026

A comprehensive analysis of the association of psychological profiling and sagittal balance parameters with neck pain in a non-deformity cervical spondylosis population: A prospective two-centers cross-sectional study.

Marco Battistelli, Sofia Vannuccini, Massimo Benenati, Mario Muselli, Nicola Montano, Massimiliano Visocchi, Gabriele Capo, Carlo Brembilla, Maurizio Fornari, Simona Gaudino and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Marco BattistelliMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy. marco.battistelli01@icatt.it.ORCID https://orcid.org/0009-0000-5784-5870
Sofia VannucciniClinical Psychology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Massimo BenenatiDipartimento Di Diagnostica Per Immagini, Fondazione Policlinico Universitario A. Gemelli IRCCS, Radioterapia, Rome, Oncologia Ed Ematologia, Italy.
Mario MuselliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Nicola MontanoMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Massimiliano VisocchiMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Gabriele CapoDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Milan, 20089, Italy.
Carlo BrembillaDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Milan, 20089, Italy.
Maurizio FornariDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Milan, 20089, Italy.
Simona GaudinoMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Francesco DogliettoMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Filippo Maria PolliMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Daniela Pia Rosaria ChieffoMedicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose to comprehensively identify determining factors of perceived neck pain in a non-deformity population, integrating psychological and sagittal balance parameters.Methods a cross-sectional study of prospectively collected data was conducted on patients admitted for cervical spondylosis at two tertiary university hospitals between April 2024 and August 2025. Eligible cases were retrieved from the PANDA Registry. Records were excluded if standing X-ray was unavailable and/or not-evaluable (e.g. shoulder prosthesis); or if the admission pathology involved the cranio-cervical junction, tumors, deformities, spinal cord disease, or infections. Preoperative data included demographic, clinical (VAS neck), psychological (SCL-27, I-TIPI, CD-RISC10), and sagittal balance variables (McGregor slope, C1-C2 lordosis, C2 slope, C2-C7 lordosis, cSVA, T1 slope, cervical mismatch). Correction for multiple comparisons was applied within pre-specified hypothesis domains.Results one-hundred-thirty records were included. Intra-rater reliability for radiographic parameters was excellent (> 0.9). After categorization of patients by neck pain severity, pairwise analysis showed that only C1-C2 lordosis remained significantly higher in patients exhibiting severe neck pain (VAS < 7 vs. VAS ≥ 7). When stratified for moderate-to-severe neck pain (VAS ≥ 4), several SCL-27 scales, namely dysthymic, vegetative, agoraphobic, sociophobic, and GSI scores, and C1C2 lordosis showed significant differences. Correlation analysis using VAS neck as the dependent variable demonstrated a significant positive correlation with SCL-27 dysthymic and vegetative scores. C1-C2 lordosis showed a significant inverse correlation with neck pain. In univariate analysis, only SCL-27 dysthymic, vegetative, and GSI scores emerged as significant univariate associations of VAS neck. After correction for multiple comparisons, the SCL-27 vegetative, dysthymic and GSI scores retained significance, whereas C1-C2 lordosis did not.Conclusion in a non-deformity population, sagittal balance parameters alone do not adequately explain patient-perceived neck pain. These findings support the preoperative use of psychological assessments, especially the SCL-27, as a useful tool in preoperative screening and individualised counselling.

Indexed as

Cervical VertebraeNeck PainPostural BalanceSpondylosisAdultAgedCross-Sectional StudiesFemaleHumansLordosisMaleMiddle AgedPain MeasurementProspective StudiesCervical sagittal balanceCervical spondylosisCross-sectional studyNeck painPsychological profiling factorsSymptom Checklist-27 (SCL-27)

Identifiers

PMID42894039
PMCPMC13677632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.