Evidence map›Paper›PMID 42894029›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2026

Longitudinal association between body weight change and brachial-ankle pulse wave velocity in patients with treated hypertension or diabetes mellitus: A post hoc analysis of the FMD-J study B.

Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Aya Mizobuchi, Farina Mohamad Yusoff, Yukiko Nakano, Yukihito Higashi

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Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Tatsuya MaruhashiDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Masato KajikawaDivision of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Japan.
Shinji KishimotoDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Takayuki YamajiDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Takahiro HaradaDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Aya MizobuchiDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Farina Mohamad YusoffDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan.
Yukiko NakanoDepartment of Cardiovascular Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Japan.
Yukihito HigashiDepartment of Regenerative Medicine, Division of Radiation Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8553, Japan. yhigashi@hiroshima-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated cross-sectional associations between body mass index (BMI) and brachial-ankle pulse wave velocity (baPWV) and longitudinal associations between body weight change and baPWV over 3 years in 874 patients with treated hypertension or diabetes mellitus without coronary artery disease (475 men; mean age, 61.9 ± 9.5 years). baPWV was measured at baseline, 1.5 years, and 3 years. At baseline, BMI was inversely correlated with baPWV (r = -0.14, P < 0.001), and multivariate analysis confirmed this association (β = -12.5, P < 0.001). In generalized linear mixed-effects models adjusted for concurrent systolic blood pressure, heart rate, and other covariates, neither continuous percentage change in body weight (β = -1.2, P = 0.08) nor categorical body weight change (≥5% increase: β = -10.6, P = 0.45; ≥5% decrease: β = 18.0, P = 0.15) was associated with longitudinal changes in baPWV, with no interaction across baseline BMI categories. The modest body weight changes observed in this cohort were not significantly associated with longitudinal changes in baPWV.

Indexed as

Arterial stiffnessBody mass indexBody weightBrachial-ankle pulse wave velocity

Identifiers

PMID42894029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.