Evidence map›Paper›PMID 42893978›Full record

ArticleNature communications2026

Automated screening of autism via a pretrained vision-language model in naturalistic caregiver-child interactions.

Ruikang Deng, Huishi Huang, Shaoli Lv, Yu Xing, Yijie Li, Cong You, Fei Wu, Hongzhu Deng, Zhengxing Huang

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ruikang Deng *College of Computer Science and Technology, Zhejiang University, Hangzhou, China.
Huishi Huang *Child Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shaoli LvChild Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yu XingChild Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yijie LiChild Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Cong YouChild Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Fei WuCollege of Computer Science and Technology, Zhejiang University, Hangzhou, China.ORCID 0000-0003-2139-8807
Hongzhu DengChild Developmental and Behavioral Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. denghzh@mail.sysu.edu.cn.ORCID 0000-0002-3919-117X
Zhengxing HuangCollege of Computer Science and Technology, Zhejiang University, Hangzhou, China. zhengxinghuang@zju.edu.cn.ORCID 0000-0002-2644-8642

Funding

Chinese Ministry of Science and Technology | Department of S and T for Social Development (Department of S&T for Social Development) No 2022YFF1202400National Natural Science Foundation of China (National Science Foundation of China) No 82272129, No 82572380
6 · The paper itself

Abstract

Early autism screening is essential for timely intervention but remains constrained by specialist dependence, costly protocols, and limited accessibility. We present Autism-CLIP, a vision-language model that automates screening from 3-min naturalistic caregiver-child interaction videos recorded in toddlers aged 15-24 months. By integrating contrastive learning, large language model-generated supervision, domain-specific architecture, and hybrid training, Autism-CLIP aligns visual behavioral cues with autism-related assessment outcomes, enabling annotation-free inference. In multicenter evaluation, Autism-CLIP achieved an AUC of 0.903 in the internal cohort (n = 103) and 0.873 in the external cohort (n = 102), outperforming conventional machine learning methods. Attention mapping highlighted clinically relevant markers, including gaze aversion and limited social reciprocity. Requiring only smartphone-captured videos without manual coding or controlled settings, Autism-CLIP offers a scalable, low-cost approach to broaden access to early autism screening and support prioritization of clinical resources.

Indexed as

Autistic DisorderCaregiversMass ScreeningChild, PreschoolFemaleHumansInfantLarge Language ModelsMachine LearningMaleVideo Recording

Identifiers

PMID42893978
PMCPMC13677709

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.