Evidence map›Paper›PMID 42893465›Full record

ArticleInternational urology and nephrology2026

Comparison of outcomes between transperitoneal and retroperitoneal robot-assisted partial nephrectomy: a systematic review and meta-analysis of comparative studies.

Guoqing Zhu, Bin Zeng, Jie Yang, Weizhen Zhu, Weichao Huang, Sheng Wang, Wei Zhang, Xingyu Xiong, Hang Xu, Lu Yang

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Guoqing Zhu *Department of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Bin Zeng *Department of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jie Yang *Department of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Weizhen ZhuDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Weichao HuangDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Sheng WangDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Wei ZhangDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xingyu XiongDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Hang XuDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China. hangxu@wchscu.cn.
Lu YangDepartment of Urology and Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China. wycleflue@scu.edu.cn.

Funding

National Key Research and Development Program 2024YFB3311703-1Natural Science Foundation of Sichuan, China 2025ZNSFSC1892the National Natural Science Foundation of China 82372831,82403963, 82170785the Postdoctor Research Fund of West China Hospital, Sichuan University 2025HXBH134
6 · The paper itself

Abstract

objectiveTo compare the perioperative and functional outcomes of transperitoneal (TP) and retroperitoneal (RP) approaches in robot-assisted partial nephrectomy (RAPN) for renal cell carcinoma (RCC).

methodsA systematic literature search of PubMed, Web of Science, Cochrane, Embase, and ClinicalTrials.gov was conducted from inception to April 2026. Comparative studies that reported the outcomes of interest between TP RAPN and RP RAPN for renal cell carcinoma were included. Pooled effective sizes, including odds ratio (OR) and weighted mean differences (WMD) with 95 confidence intervals (CI), were estimated under fixed or random effect models. Further sensitivity analyses were performed to explore potential sources of heterogeneity. The study protocol was prospectively registered on PROSPERO (CRD420261390561).

resultsA total of 32 comparative studies were included, involving 6299 patients in the TP RAPN group and 4583 in the RP RAPN group, respectively. No significant differences were observed in baseline characteristics. Patients undergoing RP RAPN had a shorter operation time (OT, WMD: 15.53 min, 95%CI 9.24-21.83, P < 0.001), lower estimated blood loss (EBL, WMD: 32.34 ml, 95%CI 21.9-42.78, P < 0.001), and shorter length of stay (LOS, WMD: 0.42 days, 95%CI 0.22-0.63, P < 0.001) compared to TP RAPN. No significant differences were observed in warm ischemia time (WIT, P = 0.24), conversion to open or radical surgery (P = 0.11 and P = 0.18, respectively), positive surgical margin (PSM, P = 0.22), overall complications (P = 0.08), major complications (the Clavien-Dindo classification ≥ 3, P = 0.32), or postoperative renal function (postoperative estimated glomerular filtration rate (eGFR): P = 0.22; postoperative 3-6 month eGFR: P = 0.49; postoperative 1-year eGFR: P = 0.55). Further sensitivity analyses validated the above findings.

conclusionsThis study suggests that the RP RAPN may be superior to TP RAPN in terms of shorter OT, lower EBL, and shorter LOS. Nevertheless, given the limitations of this analysis, these findings should be interpreted cautiously, and further well-designed randomized controlled trials are required to validate our results.

Indexed as

Partial nephrectomyRenal tumorsRetroperitonealTransperitoneal

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.