ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Oral Astilbin Nanogels Modulate Senescence-Associated CD4
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu and 2 more
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Lei Zhao *Department of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.ORCID https://orcid.org/0000-0002-2367-1355 Xinyun Zhang *Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Xue SongDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Meifang ZhaoDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, People's Republic of China.
Rongshen WangSchool of Pharmacy, Shandong Second Medical University, Weifang, Shandong, People's Republic of China.
Haocheng DuSchool of Life Science and Technology, Shandong Second Medical University, Weifang, Shandong, People's Republic of China.
Yan ChenDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Peigen XuDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Jiangyun LiuDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.ORCID https://orcid.org/0000-0002-7316-0430 Jian ZhangDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.ORCID https://orcid.org/0000-0002-4372-2826 Jingjing MaDepartment of Pharmacy, The Fourth Affiliated Hospital of Soochow University, College of Pharmaceutical Sciences, Medical Center of Soochow University, Suzhou, Jiangsu, People's Republic of China.ORCID https://orcid.org/0000-0001-6731-1266 Funding
2025 Special Research Project, Capacity Building and Continuing Education Center of the National Health Commission of China GWJJZX20251007061collaborative project with Nantong Saikon Biotechnology Co., Ltd. H250954Gusu Health Talent Program of Suzhou GSWS2025062Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology, Suzhou Vocational Health College SGK1202412National Natural Science Foundation of China 82400241Open fund of the National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery BarriersOpening Foundation of State Key Laboratory of Neurology and Oncology Drug Development SKLSIM-20251432Research Pre-research Fund Project of the Second Affiliated Hospital of Soochow University SDFEYBS2307State Key Laboratory of Advanced Drug Delivery and Release Systems DSQZ-QN-20250102Suzhou Medical College-QiLu Medical Research Program of Soochow University 24QL200212Suzhou Science and Education for Health Empowerment Project ZDXM2025010The Natural Science Foundation of the Jiangsu Higher Education Institutions of China 24KJB350009Young Talents Program of China National Nuclear Corporation
6 · The paper itselfAbstract
Inflammatory bowel disease (IBD) in older individuals is characterized by immune senescence and deteriorating intestinal homeostasis, both of which limit the efficacy of current therapies. Here, we develop fluorinated β-glucan/pectin nanogels (F
Indexed as
aged colitisastilbinCD4+ T cellscolon‐targeted deliveryoral nanogelsregulatory T cells
Identifiers
PMID42893426
PMCPMC13676816
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