Evidence map›Paper›PMID 42893188›Full record

ArticleBlood neoplasia2026

MCL1 inhibition exerts potent antileukemic activity by restoring apoptosis in T-lineage acute lymphoblastic leukemia.

Giorgia Giordano, Olivia Arnold, Diren Arda Karaoglu, Jommel Macaraeg, Kathryn Shimamoto, Arjun Dhar, Ella Postich, Hamed R Youshanlouei, Sinan Cetin, Girish Venkataraman and 7 more

Abstract read
In one paragraph

Article in Blood neoplasia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Giorgia GiordanoSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Olivia ArnoldSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Diren Arda KaraogluSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Jommel MacaraegSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Kathryn ShimamotoSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Arjun DharSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Ella PostichSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Hamed R YoushanloueiSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Sinan CetinSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Girish VenkataramanDepartment of Pathology, The University of Chicago, Chicago, IL.
Anand A PatelSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Adam DuVallSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Michael W DrazerSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
David T TeacheyDivision of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
James L LaBelleDepartment of Pediatrics, The University of Chicago, Chicago, IL.
Wendy StockSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Caner SayginSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI THOMAS F GAJEWSKI · 1985 to 2026
$122.1M
Reprograming T cell function through BCL-2 family protein:protein disruptionR01CA308067 · NCI · UNIVERSITY OF CHICAGO · PI James Laurence LaBelle · 2026 to 2026
$588k
Role of SASH3 in normal and malignant T cellsR37CA309658 · NCI · UNIVERSITY OF CHICAGO · PI Caner Saygin · 2026 to 2026
$451k
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA308067NCI NIH HHS R37 CA309658
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42893188
PMCPMC13676114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.