ArticleCureus2026
Ketamine Infusion Protocol for the Treatment of Complex Regional Pain Syndrome.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report presents a 57-year-old gentleman with treatment-resistant complex regional pain syndrome (CRPS) following upper limb amputation. Despite numerous interventions, including medications, nerve blocks, and spinal cord stimulators, his pain remained refractory. Four weekly ketamine infusions were administered, resulting in a notable 50% reduction in CRPS-associated pain persisting for up to four weeks post-treatment. The case demonstrates ketamine infusion therapy's potential in managing refractory CRPS, suggesting it is a promising option for patients unresponsive to conventional treatments. This case particularly highlights the use of ketamine infusion in a non-optimal circumstance with repeated weekly treatments, while most prior research has taken place primarily in an inpatient setting with continuous or daily treatments. Further research is needed to optimize dosing protocols and evaluate long-term efficacy and safety.
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Registered trials
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