ReviewCureus2026
Occupational Pesticide Exposure and Risk of Non-melanoma Skin Cancer Among U.S. Adults: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-melanoma skin cancer (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is the most common cancer diagnosed in the United States. Although ultraviolet (UV) radiation is the major risk factor, occupational exposure to pesticides has been proposed as an additional contributor among agricultural and other outdoor workers. This systematic review evaluated the available evidence on the association between occupational pesticide exposure and the risk of NMSC among U.S. adults. Following PRISMA 2020 guidelines, PubMed, the Excerpta Medica database (Embase), Web of Science, and the Cochrane Library were searched for eligible observational studies published between 2015 and March 2026. Study quality was assessed using the Newcastle-Ottawa Scale (NOS). The search yielded 490 records, and 26 studies met the inclusion criteria. Across the included studies, workers with prolonged pesticide exposure, frequent dermal contact, longer employment in agricultural settings, and inconsistent use of personal protective equipment generally had a higher risk of NMSC. Several studies also described biological mechanisms, including oxidative stress, chronic inflammation, and DNA damage, that may explain this relationship. However, differences in exposure assessment and the influence of concurrent ultraviolet exposure limited direct comparisons between studies. Current evidence supports an association between long-term occupational pesticide exposure and increased NMSC risk, but additional prospective studies using more accurate exposure measurements are needed to strengthen the evidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.