Evidence map›Paper›PMID 42892933›Full record

ReviewOpen respiratory archives2027

Future Treatments for Tobacco Dependence.

Carlos Andrés Jimenez-Ruiz, Maria Isabel Cristóbal Fernández, Jose Ignacio de Granda-Orive, Angela Ramos-Pinedo, Carlos Rábade-Castedo, Francisco Carrion-Valero, Inmaculada Gorordo-Unzueta, Juan Antonio Riesco-Miranda

Abstract readReview
In one paragraph

Review in Open respiratory archives, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlos Andrés Jimenez-RuizUnidad de Tabaquismo. Madrid, Spain.
Maria Isabel Cristóbal FernándezUnidad Especializada en Tabaquismo, Servicio de Neumología, Hospital Clínico San Carlos, Madrid, Spain.
Jose Ignacio de Granda-OriveUnidad de Tabaquismo, Servicio de Neumologia, Hospital Universitario 12 de Octubre, Madrid, Spain.
Angela Ramos-PinedoUnidad de Tabaquismo, Servicio de Neumología, Hospital Fundación Alcorcón, Madrid, Spain.
Carlos Rábade-CastedoUnidad Especializada en Tabaquismo, Servicio de Neumologia, Hospital Clínico Santiago de Compostela, La Coruña, Spain.
Francisco Carrion-ValeroServicio de Neumología, Hospital Universitario La Fe, Valencia, Spain.
Inmaculada Gorordo-UnzuetaUnidad de Tabaquismo, Servicio de Neumología, Hospital de Galdakao, Bilbao, Spain.
Juan Antonio Riesco-MirandaUnidad Especializada en Tabaquismo, Servicio de Neumología, Hospital San Pedro de Alcántara, Cáceres, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientific evidence supports that the combination of psychological counseling and pharmacological treatment is the most effective healthcare intervention to help smokers quit. Four types of medications have been shown to be safe and effective: nicotine replacement therapy (NRT), bupropion, varenicline, and cytisinicline. Nevertheless, based on the results of new studies, we can point out several opportunities for development clinical research in this field: (a) finding the most effective doses for cytisinicline, (b) finding the effectiveness and safety of cytisinicline in smokers with chronic disorders, (c) comparing the effectiveness and safety of cytisinicline at higher doses with varenicline at standard doses, (d) investigating the effectiveness and safety of varenicline and cytisinicline used at standard doses but in different pharmaceutical formulations, (e) comparing the effectiveness and safety of cytisinicline at higher doses with nicotine replacement combined treatment, (f) determining the effectiveness and safety of smoking cessation medications as a treatment for new tobacco and nicotine products users (electronic cigarettes and heated tobacco users), (g) to determine the effectiveness and safety of combining pharmacological treatment for smoking cessation with non-invasive brain stimulation, and (h) to optimize the efficacy and safety of smoking cessation medications based on nicotine metabolite ratio (NMR) and probably the most recent suggestion to determine the efficacy and safety of glucagon-like peptide-1 (GLP-1) receptor agonists. All these aspects will be discussed in this paper.

Indexed as

Clinical researchPharmacological treatmentSmoking cessation

Identifiers

PMID42892933
PMCPMC13675915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.