Evidence map›Paper›PMID 42892776›Full record

ArticleDiabetes, obesity, and cardiometabolic CARE

Determinants of Cognitive Change Over 1 Year in Older Adults With Type 1 Diabetes.

Miranda Zuniga-Kennedy, Justin Gillette, Hariharan Malmurugan, Jacob Satake, Anjali Sharma, Anika Bilal, Anna Casu, Robert J Henderson, Yogish C Kudva, Richard Pratley and 1 more

Abstract read
In one paragraph

Article in Diabetes, obesity, and cardiometabolic CARE. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miranda Zuniga-KennedyPsychology Department, Washington State University, Pullman, WA.ORCID https://orcid.org/0000-0002-9723-8837
Justin GilletteElson S. Floyd College of Medicine, Washington State University, Spokane, WA.
Hariharan MalmuruganElson S. Floyd College of Medicine, Washington State University, Spokane, WA.
Jacob SatakeElson S. Floyd College of Medicine, Washington State University, Spokane, WA.
Anjali SharmaElson S. Floyd College of Medicine, Washington State University, Spokane, WA.
Anika BilalAdventHealth Translational Research Institute, Orlando, FL.ORCID https://orcid.org/0000-0003-4401-1222
Anna CasuAdventHealth Translational Research Institute, Orlando, FL.
Robert J HendersonJaeb Center for Health Research, Tampa, FL.
Yogish C KudvaMayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0003-0285-6622
Richard PratleyAdventHealth Translational Research Institute, Orlando, FL.
Naomi ChaytorElson S. Floyd College of Medicine, Washington State University, Spokane, WA.ORCID https://orcid.org/0000-0001-8821-289X

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
A Randomized Cross-Over Trial Evaluating Automated Insulin Delivery Technologies on Glycemic Outcomes and Quality of Life in Older Adults with Type 1 DiabetesR01DK122603 · NIDDK · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI CHAYTOR, NAOMI SAGE, HENDERSON, ROBERT J · 2019 to 2023
$2.8M
NCATS NIH HHS UL1 TR001878NIDDK NIH HHS R01 DK122603
6 · The paper itself

Abstract

objectiveOlder adults with type 1 diabetes (T1D) have a greater risk for cognitive decline, highlighting the need to identify risk factors for meaningful cognitive change using brief screening tools suitable for annual wellness examinations. RESEARCH DESIGN AND

methodsThis study examined determinants of 1-year cognitive change in 74 older adults with T1D (mean age 70 ± 4 years; 47% female). Cognitive outcomes included the Montreal Cognitive Assessment (MoCA) and the Processing Speed Index (PSI) from the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Bivariate correlations and multiple regression analyses evaluated demographic, vascular, and diabetes-related predictors.

resultsThe mean MoCA change score was 0.1 (range -5 to 7; 23% with >1.73-point lower scores after 12 months), and the mean change on the WAIS-PSI was 2.5 (range -14 to 28). Greater MoCA decline was seen in participants with neuropathy (

conclusionsPartnered status, older age, hypertension, neuropathy, and interval severe hypoglycemia predicted 1-year cognitive decline detectable with brief cognitive screening and processing speed measures, underscoring the importance of cognitive assessment and monitoring in older adults with T1D who present with these risk factors. f0eb95da-ff7b-4b60-9495-bc32be08ad8ddoc260069video1.

Identifiers

PMID42892776
PMCPMC13675391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.