Evidence map›Paper›PMID 42892685›Full record

ArticleBMC oral health2026

Attenuation of cyclophosphamide toxicity by protective effects of curcumin in albino rats model.

Noura Mohammed Bakr, Abeer Abdel Maksoud, Nehad Abdelmawgoud Ahmad

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noura Mohammed BakrFaculty of dental medicine for girls, Al-azhar university, Cairo, Egypt.
Abeer Abdel MaksoudFaculty of dental medicine Fayoum university, Fayoum, Egypt.
Nehad Abdelmawgoud AhmadFaculty of dental medicine for girls, Al-azhar university, Cairo, Egypt. Nehadmuhammed.26@azhar.edu.eg.ORCID http://orcid.org/0000-0002-1687-6862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemotherapy primarily treats cancer by using drugs to kill cancer cells. Curcumin, a natural adjuvant, shows promise in preventing side effects. PURPOSE: This study seeks to determine curcumin's protective effect against cyclophosphamide toxicity. MATERIALS AND

methodsTwenty-one male albino rats were used in this study, divided into three groups of seven. Group I received daily oral saline. Group II was given a single dose of CP (200 mg/kg) after seven days of saline with 0.5% CMC. Group III received CP (200 mg/kg) on day seven following seven days of CUR (30 mg/kg/day). At the experiment's conclusion, the rats were euthanized under anesthesia, and their parotid salivary glands were collected.

resultsThe control group showed normal architecture. In group II, histological changes included necrosis of serous acini, striated duct, and atrophy of some acini cells. Group III displayed slight improvement in cell architecture. Cytochrome.

conclusionThe study examined Curcumin's role in preventing Cyclophosphamide-induced changes.

Indexed as

Antineoplastic Agents, AlkylatingCurcuminCyclophosphamideAnimalsMaleParotid GlandRatsAntineoplastic Agents, AlkylatingCurcuminCyclophosphamideChemotherapyCurcuminCyclophosphamideImmunohistochemical studyTEM

Identifiers

PMID42892685
PMCPMC13676792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.