ReviewMolecular biology reports2026
Adhesion gateway: decoding mechanobiological cues for cytoskeletal reconfiguration.
Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
Cellular adhesion is a central determinant of functional three-dimensional tissue structures. The challenges lie in restoring stable cell-to-cell and cell-to-matrix adhesion from dissociated cells without compromising cell integrity and impairing the ability of cells to form functional 3D structures. Recent breakthroughs have elucidated diverse, force-sensitive mechanisms for inducing cellular adhesion, providing a foundation for advanced therapeutic and engineering applications. This review provides a comprehensive analysis of recent work on individual mechanosensing and mechanotransduction pathways governing cellular adhesion. Collectively, we integrate several mechanical stimulation strategies, chemotransduction, adhesion-associated molecular networks, and AFM-based quantitative methodologies into a unified framework centered on the experimental toolbox used in adhesion mechanobiology. We further encompass the full spectrum of mechanobiology, starting from various mechanobiological cues (such as mechanical stimuli, micropatterning, stretch-induced adhesion, and biochemical strategies) and the role of molecular players (like integrin, vinculin, talin, actin, cadherin, and beyond) in focal adhesion. Downstream effects of gene expression, cellular responses to different surface stiffness, and the methodological approaches of bio-atomic force microscopy (Bio-AFM) and diverse modes of external stimulation were highlighted.
Indexed as
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42891907What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.