Evidence map›Paper›PMID 42891896›Full record

ArticleClinical and experimental nephrology2026

Dietary energy and protein intake assessed based on meal intake rate at dialysis initiation might be associated with 2-year mortality and hospitalization.

Yoshifumi Hamasaki, Mai Fujiwara, Mikie Imafuku, Kana Suzuki, Marie Morota, Teruhiko Yoshida, Yohei Komaru, Masaomi Nangaku

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Article in Clinical and experimental nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Yoshifumi Hamasaki *Department of Hemodialysis and Apheresis, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. yhamasaki-tky@umin.ac.jp.ORCID http://orcid.org/0000-0003-1874-1846
Mai Fujiwara *Clinical Nutrition Center, The University of Tokyo Hospital, Tokyo, Japan.
Mikie ImafukuDepartment of Hemodialysis and Apheresis, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Kana SuzukiDepartment of Hemodialysis and Apheresis, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Marie MorotaDepartment of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan.
Teruhiko YoshidaDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan.
Yohei KomaruDepartment of Emergency and Critical Care Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Masaomi NangakuDepartment of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary intake assessment is necessary for developing appropriate nutritional management aimed at improving patient outcomes. We investigated the association of dietary intake at dialysis initiation, as calculated using data of meal intake rates, with adverse outcomes.

methodsData were collected retrospectively from patients starting hemodialysis (HD) or peritoneal dialysis (PD) during 2016-2018. Dietary energy intake (DEI) and dietary protein intake (DPI) were calculated based on data of nutritional contents of meals provided for patients and meal intake rates recorded by nurses during three days from dialysis initiation. We assessed the association between each of DEI and DPI and primary outcomes: death and hospitalization within 2 years.

resultsThis study examined 114 patients starting HD or PD, with median age of 72 (72% male). Cox proportional hazards analyses showed DEI and DPI as associated independently with the primary outcome. Hazard ratios and 95% confidence intervals were 0.94 and 0.91-0.98 for DEI, and 0.22 and 0.09-0.53 for DPI. The relation between each of DEI and DPI and outcomes held true in each subgroup with unplanned dialysis initiation and with pre-frail or frail condition. Receiver operating characteristic analysis results suggest cut-off values of 24.0 kcal/kg/day of DEI and 0.9 g/kg/day of DPI to predict the primary outcome.

conclusionDEI and DPI, as calculated using data of meal intake rates, are associated independently with 2-year mortality and hospitalization in patients starting dialysis. Patients with unplanned dialysis initiation and with pre-frail or frail condition should be prioritized for nutritional assessment.

Indexed as

Dietary energy intakeDietary protein intakeHospitalizationMeal intake ratesMortality

Identifiers

PMID42891896

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