Evidence map›Paper›PMID 42891879›Full record

ReviewBiodegradation2026

Microalgae-based removal and biodegradation of antibiotics: mechanisms, synergistic consortia, and engineering prospects.

Jun Liu, Jiajie Zhang, Menglei Jiang, Xinru Lin, Cuiying Peng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biodegradation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun LiuDepartment of Cell Biology and Genetics, Institute of Cytology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, No. 28, Changsheng West Road, Hengyang City, 421001, Hunan, China. 1999001787@usc.edu.cn.ORCID https://orcid.org/0000-0002-7165-1359
Jiajie ZhangDepartment of Cell Biology and Genetics, Institute of Cytology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, No. 28, Changsheng West Road, Hengyang City, 421001, Hunan, China.
Menglei JiangDepartment of Cell Biology and Genetics, Institute of Cytology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, No. 28, Changsheng West Road, Hengyang City, 421001, Hunan, China.
Xinru LinDepartment of Cell Biology and Genetics, Institute of Cytology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, No. 28, Changsheng West Road, Hengyang City, 421001, Hunan, China.
Cuiying PengDepartment of Cell Biology and Genetics, Institute of Cytology and Genetics, School of Basic Medical Sciences, Hengyang Medical School, University of South China, No. 28, Changsheng West Road, Hengyang City, 421001, Hunan, China.

Funding

Hunan Provincial Natural Science Foundation of China 2025JJ50152
6 · The paper itself

Abstract

Antibiotic pollution in aquatic environments drives the spread of resistance genes and threatens ecosystem health. Microalgae offer a dual-function platform that both senses antibiotic stress and actively removes these contaminants. This review synthesizes current knowledge on microalgae-based antibiotic removal and biotransformation, emphasizing the integration of biosorption, enzyme-mediated transformation-primarily via cytochrome P450 and nitroreductase-and co‑metabolic processes. We highlight the phycosphere as a dynamic interface where symbiotic bacteria enhance algal survival and pollutant removal, while also modulating the enrichment and dissemination of resistance genes. Algal-bacterial granular sludge systems illustrate the practical potential of this synergy, achieving efficient antibiotic removal and suppression of resistance propagation. Emerging tools such as immobilization, synthetic biology, and machine learning show potential to further improve system robustness and may facilitate precision process control, although their scalability and long-term performance remain to be validated. By linking fundamental mechanisms with engineering strategies, this review provides a framework for developing sustainable, low-carbon bioremediation technologies aligned with global antimicrobial resistance action plans.

Indexed as

Anti-Bacterial AgentsMicroalgaeWater Pollutants, ChemicalBacteriaBiodegradation, EnvironmentalAnti-Bacterial AgentsWater Pollutants, ChemicalAlgal–bacterial consortiumAntibiotic removalAntibiotic resistance genesBiotransformationEnzymatic biotransformationMicroalgaeWastewater bioremediation

Identifiers

PMID42891879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.