SynthesisJournal of obesity2026
Quality of Life in Adults With Severe Obesity: A Systematic Review and Meta-Analysis of Cross-Sectional Studies.
Synthesis in Journal of obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeThis systematic review aimed to synthesize evidence on the association between severe obesity (body mass index [BMI] ≥ 40 kg/m
methodsCohort and cross-sectional studies published up to March 2024 were eligible. The review protocol was registered in PROSPERO (CRD42023374612). PubMed, Embase, Scopus, Web of Science, SciELO, CINAHL, and LILACS were searched. Two independent reviewers selected studies, extracted data, and assessed methodological quality using the National Heart, Lung, and Blood Institute tool. Findings were synthesized narratively and through an exploratory random-effects meta-analysis of absolute SF-36 mean scores.
resultsTwenty cross-sectional studies were included. The SF-36 and its variations were the most frequently used instruments. Across studies with BMI comparison groups, higher BMI categories were generally associated with lower QoL scores. The lowest scores were most consistently observed for physical functioning, role due to physical health, bodily pain, and general health. Among the mental health-related domains, vitality showed the most consistently reduced scores. Between-study heterogeneity was high for most pooled estimates.
conclusionAcross the available cross-sectional evidence, adults with severe obesity generally had lower QoL, particularly in physical domains. However, substantial heterogeneity and the absence of longitudinal evidence limit certainty and preclude causal interpretation. Longitudinal studies using standardized QoL measures are needed.
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