ArticleJournal of medical physics
Assessment of Calculation Grid Size Impact on Plan Quality and Gamma Evaluation Metrics in Intracranial Stereotactic Radiotherapy.
Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Background: This study aimed to evaluate the impact of dose calculation grid size on dosimetric accuracy, plan quality indices, and patient-specific quality-assurance (QA) outcomes in intracranial stereotactic radiotherapy (SRT). Materials and Methods: Fifteen retrospective intracranial SRT plans treated with HyperArc volumetric modulated arc therapy were re-planned using five dose calculation grid sizes of 1.0, 1.25, 1.5, 1.75, and 2.0 mm in the Eclipse treatment planning system. All plans were made to deliver 30 Gy in 5 fractions using 6 MV flattening-filter-free beams and calculated using the Anisotropic analytical algorithm. Plan quality was evaluated using multiple plan quality metrics, including RTOG quality coverage index (QI), Paddick conformity index, homogeneity index, and gradient index (GI). Dose spillage outside the target was assessed using volumetric dose indices. Patient-specific QA was performed using SRS MapCHECK with gamma-analysis under multiple criteria. Statistical comparisons were conducted using dependent paired Results: Increasing the dose calculation grid size resulted in a systematic increase in planning target volume mean dose and a corresponding reduction in D Conclusion: Study highlights that dose grid size variations significantly influence dosimetric accuracy, plan quality, and QA robustness in intracranial SRT. Coarser calculation grids compromise target coverage and gradient fidelity, while finer grids (≤1.25 mm) preserve near-reference dosimetric accuracy. Adopting a finer calculation grid ensures reliable dose computation, consistent patient-specific QA, and optimal clinical performance in SRT.
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