Evidence map›Paper›PMID 42891445›Full record

ArticleAdvanced biomedical research2026

Protective Role of

Elham Karimi-Sales, Khalil Hajiasgharzadeh, Parviz Shahabi, Mohammad Reza Alipour

Abstract read
In one paragraph

Article in Advanced biomedical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elham Karimi-SalesStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khalil HajiasgharzadehStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Parviz ShahabiDepartment of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Reza AlipourDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is a growing health concern, with an increasing prevalence. Overconsumption of a high-fat diet (HFD) is a risk factor for various diseases, including chronic kidney disease. Chronic HFD intake appears to be connected with ectopic deposition of lipids in the kidney, induction of endoplasmic reticulum (ER) stress, and renal dysfunction. Materials and Methods: Twenty-one male Wistar rats were grouped into three groups: (1) control received 10% Tween 80, (2) HFD received a liquid HFD (10 mL/kg) and 10% Tween 80, and (3) HFD plus chalcone received a liquid HFD and Results: Feeding with HFD significantly increased the atherogenic index (CRI-II) and the expression levels of FABP4, GRP78, and CHOP in the kidneys of animals. Conversely, Conclusion:

Indexed as

Endoplasmic reticulum stressfatty acid-binding protein 4kidneyTrans-chalcone

Identifiers

PMID42891445
PMCPMC13675013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.