ArticleAdvanced biomedical research2026
Guillain-Barré Syndrome (GBS) as a COVID-19 Complication: A Multicenter Study Conducted Throughout the 2-Year Pandemic.
Article in Advanced biomedical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Several studies have been published on the coexistence of Guillain-Barré syndrome (GBS) and COVID-19, raising the question of whether SARS-CoV-2 plays a role in GBS pathogenesis or is just a coincidence. In this research, we discuss GBS characteristics in COVID-19 patients during the pandemic. Material and Methods: This cross-sectional, multi-center study was performed on patients who were hospitalized in one of two GBS referral hospitals in Isfahan Providence between March 2020 to March 2022. All confirmed GBS and COVID-19 patients with no other known risk factor for GBS and no more than 28 days of COVID-19 treatment were entered into the trial. Results: Totally, 45 patients were collected. The most prevalent EDX pattern was AIDP (57.8%). As compared to demyelinating injuries, axonal injuries were significantly more associated with lung involvement ( Conclusion: An earlier onset of neurological symptoms and para-infection conditions is associated with an increase in the frequency of axonal-type variations and, as a result, a poor prognosis. The majority of evidence in COVID-19-related GBS patients points to an autoimmune process.
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