ArticleEuropean heart journal. Imaging methods and practice2026
Acute deoxygenation during M-TEER: a note of caution.
Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Right-to-left (R-L) shunting through an iatrogenic atrial septal defect (iASD) after mitral transcatheter edge-to-edge repair (M-TEER) is a rare but potentially life-threatening complication. We aimed to identify factors associated with clinically relevant R-L shunting requiring emergency iASD closure. Methods and results: We retrospectively analysed 444 consecutive patients undergoing successful M-TEER between 2017 and 2026. Clinical, echocardiographic, and invasive haemodynamic parameters were compared between patients requiring emergency iASD closure and the remaining cohort. Six patients (1.3%) required emergency iASD closure due to R-L shunting and acute deoxygenation. All presented with severe tricuspid regurgitation, RV dilatation, and impaired RV function. Following M-TEER, right atrial pressure exceeded left atrial pressure in five patients. Compared with controls, affected patients demonstrated reduced tricuspid annular plane systolic excursion (15 ± 2 vs. 19 ± 4 mm), fractional area change (FAC) (27 ± 5% vs. 43 ± 6%), and RV free wall strain (-13 ± 2% vs. -22 ± 5%). Echocardiography underestimated invasively measured systolic pulmonary artery pressure (25.8 vs. 40.3 mmHg; Conclusion: Severe tricuspid regurgitation, RV dysfunction, and elevated right atrial pressure may identify patients at risk for clinically relevant R-L shunting after M-TEER. Comprehensive RV assessment, including FAC and strain, combined with invasive hemodynamic evaluation, may improve risk stratification and facilitate timely iASD closure.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.