ArticleBioinformatics advances2026
User-driven development and evaluation of an agentic framework for analysis of large pathway diagrams.
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Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
34 authors.
Marie CorradiInnovative Testing in Life Sciences and Chemistry, HU-University of Applied Sciences Utrecht, 3584 CS Utrecht, Netherlands.ORCID https://orcid.org/0000-0001-8185-5913
Ivo DjidrovskiInstitute of Risk Assessment Sciences (IRAS), Utrecht University, 3584 CM Utrecht, Netherlands.ORCID https://orcid.org/0000-0002-7637-8515
Luiz LadeiraBiomechanics Research Unit, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID https://orcid.org/0000-0002-7152-2688
Bernard StaumontBiomechanics Research Unit, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID https://orcid.org/0000-0003-3155-4885
Anouk VerhoevenDepartment of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, 1090 Jette, Belgium.
Julen Sanz SerranoDepartment of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, 1090 Jette, Belgium.
Adrien RougnyLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0002-2118-035X
Ahmad VaezUnit of Genetic Epidemiology & Bioinformatics, Department of Epidemiology, University Medical Center Groningen, 9700 RB Groningen, Netherlands.ORCID https://orcid.org/0000-0001-9048-3795
Ahmed HemedanTransversal Translational Medicine, Luxembourg Institute of Health, L-1445 Strassen, Luxembourg.ORCID https://orcid.org/0000-0001-7403-181X
Alexander MazeinDepartment of Cancer Research, Luxembourg Institute of Health, L-1445 Strassen, Luxembourg.ORCID https://orcid.org/0000-0001-7137-4171
Anna NiarakisFaculty of Science and Engineering, Department of Biology and Geosciences, University of Toulouse, 31062 Toulouse, France.ORCID https://orcid.org/0000-0002-9687-7426
Arthur de Carvalho E SilvaCentre for Environmental Research and Justice (CERJ), School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.ORCID https://orcid.org/0000-0001-9866-3344
Charles AuffrayEuropean Institute for Systems Biology and Medicine, 69390 Vourles, France.ORCID https://orcid.org/0000-0003-2226-7411
Egon WillighagenTranslational Genomics, NUTRIM, FHML, Maastricht University, 6200 MD Maastricht, Netherlands.ORCID https://orcid.org/0000-0001-7542-0286
Eliska KuchovskaIUF - Leibniz Research Institute for Environmental Medicine, 40225 Düsseldorf, Germany.ORCID https://orcid.org/0000-0002-6611-8816
Falk SchreiberDepartment of Computer and Information Science, University of Konstanz, 78457 Konstanz, Germany.ORCID https://orcid.org/0000-0002-9307-3254
Irina BalaurLuxembourg National Data Service, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0002-3671-895X
Laurence CalzoneComputational Systems Biology of Cancer, Institut Curie, U1331 INSERM, Mines ParisTech, PSL, 75005 Paris, France.ORCID https://orcid.org/0000-0002-7835-1148
Lisa MatthewsBiochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, United States.ORCID https://orcid.org/0000-0001-5707-3065
Lorenzo VeschiniBiocomplexity Institute, Department of Intelligent Systems Engineering, Indiana University at Bloomington, Bloomington, IN 47408, United States.
Marc E GillespieDepartment of Pharmaceutical Sciences, St. John's University, Queens, NY 11439, United States.ORCID https://orcid.org/0000-0002-5766-1702
Martina KutmonMaastricht Centre for Systems Biology and Bioinformatics (MaCSBio), Maastricht University, 6229 EN Maastricht, Netherlands.ORCID https://orcid.org/0000-0002-7699-8191
Matthias KönigInstitute of Biology, Humboldt University of Berlin, 10099 Berlin, Germany.ORCID https://orcid.org/0000-0003-1725-179X
Matti van WelzenDepartment of Systems Biology and Bioinformatics, University of Rostock, 18057 Rostock, Germany.ORCID https://orcid.org/0000-0002-2486-0246
Noriko HiroiDepartment of Electrical and Electronic Engineering, Kanagawa Institute of Technology, Kanagawa 243-0292, Japan.ORCID https://orcid.org/0000-0002-0214-373X
Oxana LopataLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0003-2852-0115
Pierre KlemmerLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0009-0006-9391-1285
Rupert OverallInstitute of Biology, Humboldt University of Berlin, 10099 Berlin, Germany.ORCID https://orcid.org/0000-0002-3882-6073
Tim HoferDepartment of Chemical Toxicology, Norwegian Institute of Public Health, N-0213 Oslo, Norway.
Venkata SatagopamLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0002-6532-5880
Reinhard SchneiderLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0009-0007-3061-1864
Marc TeunisInnovative Testing in Life Sciences and Chemistry, HU-University of Applied Sciences Utrecht, 3584 CS Utrecht, Netherlands.ORCID https://orcid.org/0000-0002-3496-6669
Liesbet GerisBiomechanics Research Unit, GIGA Institute, University of Liège, 4000 Liège, Belgium.ORCID https://orcid.org/0000-0002-8180-1445
Marek OstaszewskiLuxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0003-1473-370X
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.