Evidence map›Paper›PMID 42891346›Full record

ArticleiMetaOmics2026

Diversity, transfer potential, and transcriptional activity of virus-carried antibiotic resistance genes in global estuaries.

Xiao-Qing Luo, Xiyang Dong, Jia-Ling Li, Ji-Cheng Yao, Ziqi Peng, Qi Li, Zi-Wen Yang, Yang Yuan, Wen-Jun Li, Pandeng Wang

Abstract read
In one paragraph

Article in iMetaOmics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiao-Qing LuoSchool of Pharmacy (Shenzhen University Medical School), College of Life Sciences and Oceanography, and Institute for Advanced Study, Shenzhen University Shenzhen China.ORCID https://orcid.org/0000-0002-8415-6664
Xiyang DongKey Laboratory of Marine Genetic Resources, Third Institute of Oceanography Ministry of Natural Resources Xiamen China.ORCID https://orcid.org/0000-0002-9224-5923
Jia-Ling LiSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou) Guangzhou China.ORCID https://orcid.org/0000-0002-6426-6356
Ji-Cheng YaoInstitute of Marine Biotechnology and Bio-Resource Utilization, College of Oceanography Hohai University Nanjing China.
Ziqi PengState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences Sun Yat-Sen University Guangzhou China.
Qi LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences Sun Yat-Sen University Guangzhou China.
Zi-Wen YangState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences Sun Yat-Sen University Guangzhou China.
Yang YuanInstitute of Marine Biotechnology and Bio-Resource Utilization, College of Oceanography Hohai University Nanjing China.
Wen-Jun LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Sciences Sun Yat-Sen University Guangzhou China.ORCID https://orcid.org/0000-0002-4237-6140
Pandeng WangSchool of Pharmacy (Shenzhen University Medical School), College of Life Sciences and Oceanography, and Institute for Advanced Study, Shenzhen University Shenzhen China.ORCID https://orcid.org/0000-0002-7593-6634

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estuaries, the transition zones between terrestrial and marine ecosystems, are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been considered as reservoirs and vectors of ARGs in various environments, the composition, transmission, and ecological drivers of virus-carried ARGs (vARGs) in estuarine ecosystems remain poorly understood. Here, we constructed a Global Estuarine Virome (GEV) dataset by recovering 136,443 viral operational taxonomic units (vOTUs) from 534 worldwide estuarine metagenomes. Based on this GEV dataset, we identified 282 (temperate: 217; lytic: 65) vOTUs that carried 462 ARGs. These ARGs encompassed 108 ARG subtypes conferring resistance to 13 antibiotic classes, with their richness and abundances in estuaries being directly and indirectly correlated with changes in temperatures and coastal human activities. Network approach further revealed temperature-dependent vARG transfers between viruses and prokaryotes. Moreover, ARG-carrying vOTUs could target abundant prokaryotic taxa (e.g.,

Indexed as

antibiotic resistance genesestuarine ecosystemglobal warmingvirus

Identifiers

PMID42891346
PMCPMC13674435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.