Evidence map›Paper›PMID 42891337›Full record

ArticleiMetaOmics2026

Biological age in the meta omics era: Integrating physical activity, sleep, and diet to reshape paths of healthy ageing.

Yanwei You, Yicong Cui, Yuquan Chen, Jiarong He, Dongmin Wang, Danijela Gasevic, Xifeng Wu, Steve Horvath, Mingming Zhang, Xindong Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iMetaOmics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanwei YouSaw Swee Hock School of Public Health National University of Singapore Singapore Singapore.ORCID https://orcid.org/0000-0001-8367-4980
Yicong CuiSchool of Sports Science and Engineering East China University of Science and Technology Shanghai China.
Yuquan ChenSchool of Public Health and Preventive Medicine, Faculty of Medicine, Nursing & Health Sciences, Monash University Melbourne Australia.
Jiarong HeDepartment of Neurosurgery The Second Xiangya Hospital, Central South University Changsha China.
Dongmin WangDepartment of Physical Education Peking University Beijing China.
Danijela GasevicSchool of Public Health and Preventive Medicine, Faculty of Medicine, Nursing & Health Sciences, Monash University Melbourne Australia.ORCID https://orcid.org/0000-0001-5976-4011
Xifeng WuCenter of Clinical Big Data and Analytics of The Second Affiliated Hospital, and School of Public Health Zhejiang University School of Medicine Hangzhou China.ORCID https://orcid.org/0000-0003-2980-8129
Steve HorvathHuman Genetics, David Geffen School of Medicine University of California Los Angeles California USA.
Mingming ZhangDepartment of Neurosurgery The Second Xiangya Hospital, Central South University Changsha China.ORCID https://orcid.org/0009-0006-3885-621X
Xindong MaDivision of Sports Science & Physical Education Tsinghua University Beijing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological age provides a translational endpoint linking modifiable lifestyle behaviors-physical activity, sleep, and diet-to multi-omics changes and downstream clinical outcomes. Integrating multiple ageing clocks with inflammatory, metabolic, and oxidative pathways supports reproducible, intervention-ready strategies to slow ageing and extend healthspan.

Identifiers

PMID42891337
PMCPMC13674388

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.