Evidence map›Paper›PMID 42891315›Full record

ArticleiMetaOmics2026

Microbial influences on immune modulation and colorectal cancer progression through combined transcriptomic and microbiomic analysis.

Shuting Xia, Likun Wang, Yangzhuo Xu, Jiaqi Zhang, Zeyang Zhou, Libing Sun, Heng Li, Chungen Xing, Jialu Mao, Yina Liu and 5 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in iMetaOmics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shuting XiaDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.ORCID https://orcid.org/0000-0003-2577-4339
Likun WangDepartment of Public Health, School of Public Health, Suzhou Medical College Soochow University Suzhou China.
Yangzhuo XuDepartment of Public Health, School of Public Health, Suzhou Medical College Soochow University Suzhou China.
Jiaqi ZhangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Zeyang ZhouDepartment of General Surgery The Second Affiliated Hospital of Soochow University Suzhou China.
Libing SunDepartment of Pathology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School Nanjing Medical University Suzhou China.
Heng LiDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.ORCID https://orcid.org/0000-0003-1449-6003
Chungen XingDepartment of General Surgery The Second Affiliated Hospital of Soochow University Suzhou China.
Jialu MaoDepartment of General Surgery The Second Affiliated Hospital of Soochow University Suzhou China.
Yina LiuDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Fulin YangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Ling ZhongDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Jiancheng XuDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Xiaodong YangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.
Zhemin ZhouDepartment of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Cancer Institute, Suzhou Medical College Soochow University Suzhou China.ORCID https://orcid.org/0000-0001-9783-0366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schematic representation of the distinct tumor microenvironment characteristics in CA1 and CA2 subtypes. CA1 illustrates an immune-active tumor microenvironment characterized by elevated infiltration of immune cells, particularly CD8 + T cells and macrophages, and enhanced IFN-γ signaling. This subtype shows enrichment of specific bacterial species (including

Identifiers

PMID42891315
PMCPMC13674408

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.