ArticleRSC advances2026
Nickel-catalysed synthesis of symmetrical and unsymmetrical 2,2'-bipyridines
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A nickel-catalysed cross-electrophile coupling (XEC) of 2-halopyridines to form 2,2'-bipyridines and 2,2'-bisquinoline is presented using manganese as the reductant. The method tolerates electron-donating and electron-withdrawing groups around the heterocyclic ring and has been applied to the preparation of homo- and cross-coupled products, including competition experiments. Finally, scaling-up the reaction revealed certain practical considerations that led to deviation from the optimised conditions and provided preliminary mechanistic insights.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.