ArticleFrontiers in medicine2026
Tip perfusion index for monitoring perioperative stress responses in patients undergoing laparoscopic cholecystectomy: a prospective cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to characterize peri-stimulus changes in the Tip Perfusion Index (TPI) and conventional hemodynamic parameters during elective laparoscopic cholecystectomy and to compare their response dynamics among patients without major comorbidities, patients with hypertension, and patients with type 2 diabetes mellitus. Methods: Ninety patients undergoing elective laparoscopic cholecystectomy were prospectively enrolled and classified as Control, Hypertension, or Diabetes ( Results: Demographic and baseline parameters were comparable among the three groups ( Conclusion: TPI showed consistent peri-stimulus changes during endotracheal intubation and pneumoperitoneum and may provide complementary information on peripheral vascular responses during surgical stress. The prolonged threshold-based TPI response time observed in patients with diabetes during pneumoperitoneum suggests a potential difference in response timing that warrants further investigation.
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