Evidence map›Paper›PMID 42890607›Full record

ArticleACS polymers Au2026

Benefits of Pyrenemethanol as an Initiator for the ROP of Morpholine-2,5-Diones: Fluorescence Probing of Nanoparticle Degradation and Cellular Uptake.

Johanna Schreiber, Lea C Klepsch, Jana Ismail, David Pretzel, Antje Vollrath, Christine Weber, Ulrich S Schubert

Abstract read
In one paragraph

Article in ACS polymers Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johanna SchreiberLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.ORCID https://orcid.org/0009-0000-0991-8967
Lea C KlepschLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.
Jana IsmailLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.
David PretzelLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.
Antje VollrathLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.
Christine WeberLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.ORCID https://orcid.org/0000-0003-0712-5255
Ulrich S SchubertLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, Jena 07743, Germany.ORCID https://orcid.org/0000-0003-4978-4670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1-Pyrenemethanol was used as an initiator for the ring-opening polymerization (ROP) of three morpholine-2,5-diones, which are based on the naturally occurring amino acids l-phenylalanine, l-isoleucine, and l-valine. A catalytic system consisting of 1,8-diazabicyclo[5.4.0]-undec-7-ene (DBU) and 1-(3,5-bis-(trifluoromethyl)-phenyl)-3-cyclohexylthiourea (TU) was applied for the polymerizations at room temperature. Kinetic studies demonstrated controlled reaction conditions and the absence of transesterification under the selected parameters. By means of

Indexed as

degradationfluorescencemorpholine-2,5-dionenanoparticlepoly(ester amide)pyrenering-opening polymerization

Identifiers

PMID42890607
PMCPMC13673884

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.