Evidence map›Paper›PMID 42890606›Full record

ArticleFrontiers in immunology2026

Targeting the capsule of

Nataly P Podolnikova, Iryna Klymenko, James Alagna, Cyrus Diercksmeier, Arnat Balabiyev, David Richardson, Tatiana P Ugarova

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nataly P PodolnikovaFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.
Iryna KlymenkoFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.
James AlagnaFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.
Cyrus DiercksmeierFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.
Arnat BalabiyevFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.
David RichardsonbioSyntagma Inc., Tempe, AZ, United States.
Tatiana P UgarovaFrom the School of Life Sciences, Arizona State University, Tempe, AZ, United States.

Funding

The role of beta 2 integrins in macrophage fusionR01HL063199 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI Tatiana P Ugarova · 1999 to 2026
$8.6M
NHLBI NIH HHS R01 HL063199
6 · The paper itself

Abstract

Platelet Factor 4 (PF4), a cationic antimicrobial peptide, serves as a ligand for the myeloid-specific phagocytic receptor CR3 (Mac-1, CD11b/CD18). We previously demonstrated that recombinant dimeric PF4 (rPF4) functions as a bacterial opsonin, enhancing phagocytosis of Gram-positive

Indexed as

Bacterial CapsulesKlebsiella InfectionsKlebsiella pneumoniaeMacrophage-1 AntigenPhagocytosisSepsisAnimalsCell LineDisease Models, AnimalFemaleHumansMacrophagesMiceMice, Inbred C57BLNeutrophilsMacrophage-1 Antigenantibiotic resistancebacterial capsuleCR3Klebsiella pneumoniaeMac-1PF4phagocytosis

Identifiers

PMID42890606
PMCPMC13671991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.