Evidence map›Paper›PMID 42890587›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

Right ventricular strain analysis in acute pulmonary embolism and its role for late complications.

Ioannis T Farmakis, Lina-Marie Brandes, Karsten Keller, Gerald S Laux-Winter, Sara Bombace, Philipp Lurz, Stavros V Konstantinides, Lukas Hobohm

Abstract read
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Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Temporal interpretation of right ventricular strain after pulmonary embolism.European heart journal. Imaging methods and practice · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ioannis T FarmakisCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID https://orcid.org/0000-0002-0586-6386
Lina-Marie BrandesDepartment of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Karsten KellerCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID https://orcid.org/0000-0002-0820-9584
Gerald S Laux-WinterDepartment of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Sara BombaceDepartment of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Philipp LurzDepartment of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Stavros V KonstantinidesCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID https://orcid.org/0000-0001-6359-7279
Lukas HobohmCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.ORCID https://orcid.org/0000-0002-4312-0366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Acute pulmonary embolism (PE) can result in long-term complications, including post-PE impairment (PPEI) and chronic thromboembolic pulmonary hypertension (CTEPH). Right ventricular global longitudinal strain (RVGLS) is a sensitive measure of RV myocardial deformation that may detect subclinical dysfunction and predict adverse outcomes; however, its value in the follow-up of post-PE assessment has not been yet elucidated. Methods and results: In this prospective sub-study of the FOCUS cohort, 175 consecutive PE survivors from the Mainz centre underwent echocardiographic follow-up at 3 and 12 months, including speckle-tracking assessment of RVGLS, RV free wall strain (RVFWLS), and strain-derived ventriculoarterial coupling indices. Conventional RV parameters, volumetric measures, and clinical outcomes were recorded. Overall, 175 patients were included, of whom 16 developed PPEI or CTEPH during follow-up. RV function improved over time in patients without PPEI/CTEPH, including increases in RVGLS (from -16 to -18%), RVFWLS, ejection fraction, and strain-based ventriculoarterial coupling, accompanied by reductions in RV volumes. In contrast, patients who developed PPEI/CTEPH ( Conclusion: RV strain and strain-derived ventriculoarterial coupling may provide sensitive early markers of maladaptive RV remodelling after acute PE and were associated with the development of PPEI/CTEPH, highlighting their potential value in post-PE follow-up strategies.

Indexed as

CTEPHpost-PE impairmentpulmonary embolismRV systolic strainventriculoarterial coupling

Identifiers

PMID42890587
PMCPMC13673565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.