Evidence map›Paper›PMID 42890539›Full record

ArticleFrontiers in microbiology2026

Structural and functional characterization of the gut microbiota in women with early pregnancy loss in Northwest China.

Hui Yao, Juanjuan Chen, Cai Liu, Juanjuan Huang, Ling Liu, Qi Wang, Fang Wang

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Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui Yao *The Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Juanjuan Chen *The Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Cai LiuThe Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Juanjuan HuangThe Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Ling LiuThe Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Qi WangThe Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
Fang WangThe Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early pregnancy loss (EPL) is a common adverse pregnancy outcome with a complex and incompletely understood etiology. Moreover, metagenomic studies of the gut microbiota in women with EPL in Northwest China remain limited. Objective: This study aimed to characterize differences in gut microbial composition and predicted functional potential between women with EPL (EPL group) and normal controls (NCs) using shotgun metagenomic sequencing. Methods: We collected fecal samples from 216 women in Northwest China (EPL group, Results: Our study revealed significant differences in the composition of the gut microbiota between the EPL group and NCs, as assessed by alpha and beta diversity analyses ( Conclusion: The results of our study revealed significant differences in gut microbiota composition and metabolic pathways between the EPL group and NCs, indicating that gut microbiome alterations are associated with EPL.

Indexed as

alpha diversitybeta diversitygut microbiotametagenomic sequencingpregnancy loss

Identifiers

PMID42890539
PMCPMC13671948

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.