Evidence map›Paper›PMID 42890483›Full record

ArticleFood science & nutrition2026

Neuroprotective Effects of Food-Derived Cyanidin Glycosides in an Alzheimer's Disease-Like Zebrafish Model Through Modulation of PI3K/Akt/GSK3β Signaling.

Yun Wu, Fangfang Tie, Yidan Gao, Jinze Li, Ruinan Wang, Na Hu, Qi Dong, Honglun Wang

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun WuQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.
Fangfang TieQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.ORCID https://orcid.org/0000-0002-9466-585X
Yidan GaoQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.
Jinze LiQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.
Ruinan WangQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.
Na HuQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.ORCID https://orcid.org/0000-0003-0862-3854
Qi DongQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.ORCID https://orcid.org/0000-0002-6192-1597
Honglun WangQinghai Provincial Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.ORCID https://orcid.org/0000-0002-9882-9604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder lacking effective and safe interventions. Food-derived anthocyanins have gained increasing attention due to their neuroprotective potential; however, the specific mechanisms of individual cyanidin glycosides remain insufficiently understood. Notably, the comparative efficacy and mechanistic differences among structurally distinct cyanidin glycosides have not been systematically evaluated in vivo. In the present study, three cyanidin glycosides, cyanidin-3-

Indexed as

Alzheimer's diseasecyanidin glycosidesneuroprotectionPI3K/Akt/GSK3β signaling pathwayzebrafish

Identifiers

PMID42890483
PMCPMC13671879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.