ArticlePlastic and reconstructive surgery. Global open2026
Adult-onset Still Disease Flare 5 Days Following Poly-l-lactic Acid Injection: A Cautionary Tale for Aesthetic Practice.
Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Adult-onset Still disease (AOSD) is a rare systemic autoinflammatory disorder characterized by quotidian fevers, evanescent rash, and polyarthritis. Minimally invasive aesthetic procedures are increasingly common, yet their immunological safety in patients with underlying autoimmune disease remains poorly characterized. We report a 57-year-old woman with AOSD, previously stable on annual rituximab (1 g), who developed a severe systemic flare temporally associated with a poly-l-lactic acid facial injection, with symptom onset 5 days after the procedure. She presented with high-grade pyrexia (40°C), extreme leukocytosis (white blood cell, 26 × 10
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