ArticleFrontiers in cell and developmental biology2026
Stage-specific transcriptional atlas of goose satellite cells uncovers sex-biased molecular dynamics associated with embryonic skeletal muscle development.
Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Sexual dimorphism in avian skeletal muscle is established during embryogenesis, but the stage-resolved transcriptional programs governing this process in geese remain largely unexplored. Methods: To construct a stage-specific transcriptional atlas of muscle satellite cells (SMSCs), we performed histological examination and RNA sequencing of PAX7 Results: Although myofiber morphology exhibited no overt sexual divergence, immunofluorescence revealed distinct sex- and stage-dependent dynamics, with male embryos displaying a higher PAX7 Discussion: Collectively, this transcriptional atlas delineates sex-biased molecular dynamics that operate within the Zhedong White goose SMSC pool in the absence of conspicuous histological differences, and provides a foundational gene resource for prioritizing mechanistic investigations into sexually dimorphic muscle development, focusing specifically on the embryonic leg muscles.
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