Evidence map›Paper›PMID 42890199›Full record

ArticleFrontiers in pharmacology2026

Wild ginseng adventitious roots restore sleep homeostasis in sleep-deprived

Hong Chen, Xiangzhu Li, Hang Chi, Yongjun Zheng, Yingna Li, Lu Xing, Rui Ma, Liwei Sun, Xuenan Chen

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hong ChenShanghai Jiao Tong University, Shanghai, China.
Xiangzhu LiTonghua Herbal Biotechnology Co., Ltd., Tonghua/Jilin, China.
Hang ChiTonghua Herbal Biotechnology Co., Ltd., Tonghua/Jilin, China.
Yongjun ZhengTonghua Herbal Biotechnology Co., Ltd., Tonghua/Jilin, China.
Yingna LiThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Lu XingThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Rui MaThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Liwei SunThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Xuenan ChenThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sleep deprivation is increasingly recognized as a major health concern and is associated with impaired physiological and neurological functions. Methods: The sleep-promoting effects and safety of ADV were evaluated in a sleep deprivation-induced Results: ADV significantly improved sleep behavior in sleep-deprived flies, increasing total sleep duration and deep sleep while reducing sleep latency and sleep fragmentation, without inducing addiction-like behaviors. Transcriptomic analysis revealed that ADV modulated multiple sleep-related biological processes, particularly stress response pathway, as evidenced by altered expression of Conclusion: In the

Indexed as

cellular homeostasisDrosophila melanogasterginseng adventitious rootssleep deprivationsleep regulation

Identifiers

PMID42890199
PMCPMC13672481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.