Evidence map›Paper›PMID 42890088›Full record

ArticleACS omega2026

Signaling Pathways Mediating the Cytotoxicity of (E)-4-(1-Epoxy-7,8-propenyl)phenyl Benzoate, a Phenylpropanoid from

Renata A de Abrantes, Sâmia S Duarte, Rafael C Ferreira, Ana Paula G M Farias, Geraldo M W Amorim, Paulo B A Loureiro, Ramon R M de Souza, Valgrícia M de Sousa, Gabriela B de Lyra, Isabela C F Silva and 6 more

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Renata A de AbrantesPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Sâmia S DuartePostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Rafael C FerreiraPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Ana Paula G M FariasPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Geraldo M W AmorimPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Paulo B A LoureiroPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Ramon R M de SouzaPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.ORCID https://orcid.org/0009-0002-0651-163X
Valgrícia M de SousaPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Gabriela B de LyraPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Isabela C F SilvaPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Lucas S AbreuDepartment of Organic Chemistry, Fluminense Federal University, Niterói, Rio de Janeiro 24020-141, Brazil.ORCID https://orcid.org/0000-0001-5620-8095
Eudes da S VelozoResearch Laboratory in Materia Medica, School of Pharmacy, Federal University of Bahia, Salvador, Bahia 40170-115, Brazil.
Juan C R GonçalvesPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.ORCID https://orcid.org/0000-0002-1702-1102
Marcelo S da SilvaPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.
Josean F TavaresPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.ORCID https://orcid.org/0000-0003-0293-2605
Marianna V SobralPostgraduate Program in Natural Products and Bioactive Synthetics, Federal University of Paraíba (UFPB), João Pessoa, Paraíba 58051-970, Brazil.ORCID https://orcid.org/0000-0002-7740-034X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products represent an important source of candidates for breast cancer therapy. Here, we investigated the antitumor activity of (E)-4-(1-epoxy-7,8-propen)-phenylbenzoate (CV2), a phenylpropanoid isolated from

Identifiers

PMID42890088
PMCPMC13670846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.