ArticleACS omega2026
A Microdroplet Fluorescence Method for the Determination of Nitrite in Water Using a Hydrophobic Cellulose Substrate Platform.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
In this work, a miniaturized and sustainable method was developed, based on the fluorimetric reaction with 2,3-diaminonaphthalene (DAN) in an acid medium, for the determination of trace amounts of nitrite in different water samples using a hydrophobic cellulose substrate platform. The innovation consists of the use of a nonwettable cellulose substrate that suspends stable microdroplets, enabling direct measurement of fluorescence on the front surface and mitigating the signal attenuation inherent in traditional hydrophilic paper devices. The cellulose substrate acted both as a solid support for the reaction and as a holder for microdroplet suspension during fluorescence signal acquisition. The method was designed to reduce reagent consumption and waste generation by operating at the microliter scale, using a total reaction volume of 15 μL. The procedure showed great tolerance to the presence of 11 potentially interfering ions, evaluated at concentrations relevant to water samples. The values obtained for the limit of detection were 0.35 μg L
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