Evidence map›Paper›PMID 42889990›Full record

ArticleFrontiers in oral health2026

N-

Chuang Nie, Ran Xia, Liqiong Ma, Song Li, Jing Zhang

Abstract read
In one paragraph

Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuang Nie *Anhui Provincial Key Laboratory of Oral Diseases Research, College & Hospital of Stomatology, Anhui Medical University, Hefei, China.
Ran Xia *Anhui Provincial Key Laboratory of Oral Diseases Research, College & Hospital of Stomatology, Anhui Medical University, Hefei, China.
Liqiong MaAnhui Provincial Key Laboratory of Oral Diseases Research, College & Hospital of Stomatology, Anhui Medical University, Hefei, China.
Song LiAnhui Provincial Key Laboratory of Oral Diseases Research, College & Hospital of Stomatology, Anhui Medical University, Hefei, China.
Jing ZhangAnhui Provincial Key Laboratory of Oral Diseases Research, College & Hospital of Stomatology, Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study investigated the effects of a nanocomposite comprising Materials and methods: Supragingival plaque samples were collected from 30 children aged younger than 6 years (15 males and 15 females) diagnosed with ECC. These samples were cultured Results: The Ag-Est816 composite significantly reduced microbial Conclusion: The Ag-Est816 composite suppressed several low-abundance cariogenic genera while reducing overall community richness, altered microbial metabolic functions, and compromised biofilm structural integrity. These findings indicated this non-invasive nanocomposite has potential as an adjunctive therapy for caries prevention in children.

Indexed as

biofilmsearly childhood cariesN-acyl-homoserine lactonesquorum-quenching enzymesilver nanoparticles

Identifiers

PMID42889990
PMCPMC13671943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.