ArticleACS omega2026
Oxime-Functionalized Polydiacetylene Nanocomposite Sensor for Equipment-Free On-Site Detection Of Organophosphate Insecticide Chlorpyrifos Ethyl.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A novel oxime-incorporated polydiacetylene-functionalized molecule (PCDA-OX) was synthesized for real-time, rapid, and selective detection of the organophosphate insecticide chlorpyrifos ethyl, which is widely used in agricultural fields globally. Nanocomposites containing PCDA-OX molecules were fabricated within a cellulose acetate matrix using an electrospinning technique, followed by chemical hydrolysis to obtain regenerated cellulose-based sensing materials. Comprehensive characterization was performed using scanning electron microscopy, nuclear magnetic resonance, Fourier-transform infrared spectroscopy, and an Instron tensile tester. Exposure to the chlorpyrifos ethyl triggered an instantaneous chromatic transition from blue to red/pink, enabling naked eye detection without instrumentation. The proposed sensor exhibited high selectivity against other classes of insecticides and achieved a limit of detection of 40 mmol. The sensing platform offers a simple, rapid, and field-deployable approach for organophosphate monitoring, offering a promising strategy for protecting human health and saving lives.
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