Evidence map›Paper›PMID 42889920›Full record

ArticleDiabetes, obesity, and cardiometabolic CARE

Pilot of Opportunistic Population Screening for Type 1 Diabetes at Pediatric Routine Well-Child Visits.

Matthew C Nelson, Alexis E Blackburn, Andrew Brangan, Gemme Campbell-Salome, Mushtaq A Godil, Jessica Goehringer, Lakshmi Ilango, Christie Gilbert Klaczko, Benjamin Keiser, Meredith Lewis and 9 more

Abstract read
In one paragraph

Article in Diabetes, obesity, and cardiometabolic CARE. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Matthew C NelsonPediatrics, Geisinger Health, Danville, PA.
Alexis E BlackburnGeisinger Commonwealth School of Medicine, Scranton, PA.
Andrew BranganDepartment of Genomic Health, Geisinger Health, Danville, PA.
Gemme Campbell-SalomeDepartment of Genomic Health, Geisinger Health, Danville, PA.
Mushtaq A GodilEndocrinology, Geisinger Health, Danville, PA.
Jessica GoehringerDepartment of Genomic Health, Geisinger Health, Danville, PA.
Lakshmi IlangoGeisinger Commonwealth School of Medicine, Scranton, PA.
Christie Gilbert KlaczkoDepartment of Population Health Sciences, Geisinger Health, Danville, PA.
Benjamin KeiserDepartment of Genomic Health, Geisinger Health, Danville, PA.
Meredith LewisData Core, Geisinger Health, Danville, PA.
Michelle Pistner NixonBiostatistics Core, Geisinger Health, Danville, PA.
Katrina M RomagnoliDepartment of Population Health Sciences, Geisinger Health, Danville, PA.
Allison M RosselDepartment of Genomic Health, Geisinger Health, Danville, PA.
Erin Van EnkevortDepartment of Population Health Sciences, Geisinger Health, Danville, PA.
Lauren YocumGeisinger Commonwealth School of Medicine, Scranton, PA.
Nicole L WaltersDepartment of Genomic Health, Geisinger Health, Danville, PA.
Samuel S GiddingDepartment of Genomic Health, Geisinger Health, Danville, PA.
Laney K JonesDepartment of Genomic Health, Geisinger Health, Danville, PA.
Juliann M SavattDepartment of Genomic Health, Geisinger Health, Danville, PA.ORCID https://orcid.org/0000-0001-6444-1962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAutoantibody screening for type 1 diabetes provides an opportunity to improve outcomes. Existing screening programs have not explored integration into pediatrics via opportunistic screening, i.e., screening conducted as part of another blood draw. Here, we aimed to assess the status of screening in one health system, develop a program for opportunistic screening in pediatrics, and pilot the program to assess feasibility and identify real-world barriers. RESEARCH DESIGN AND

methodsThe Geisinger system electronic health record was queried for pediatric patients who had pancreatic autoantibody testing, and relevant patients were manually reviewed to determine whether testing was completed as screening. To assess the potential of implementing opportunistic autoantibody screening into existing pediatric workflows, a pilot screening plan was implemented as an observational cohort study at a pediatric primary care clinic. Interviews were conducted to gather feedback on pilot implementation.

resultsAs of 2022, prior to the screening pilot, of 312,824 pediatric patients, 9 completed autoantibody testing as type 1 diabetes screening. An opportunistic autoantibody screening pilot was implemented in a pediatric primary care clinic between March and April 2024. During the pilot, of 120 eligible patients, 31 (26%) were enrolled and 19 (16%) completed screening. Post-pilot interviews identified barriers to screening and potential strategies to improve future implementation.

conclusionsType 1 diabetes screening was rarely performed. An opportunistic screening model in primary care was demonstrated to be feasible and could increase adoption of screening across the population with additional strategies to address identified barriers.

Identifiers

PMID42889920
PMCPMC13671883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.