Evidence map›Paper›PMID 42889903›Full record

ArticleBiomedical optics express2026

3D fast ray-traced distortion correction of indirectly viewed intraoperative retinal OCT for surgical tool path reconstruction.

Yuan Tian, Ali Torkashvand, George T Funkenbusch, Srisatya Pusuluri, Bo Hansen, Florian Kapeller, Michelle McCall, Cynthia A Toth, Anthony N Kuo, Lejla Vajzovic

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuan TianDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.ORCID https://orcid.org/0000-0001-6170-7155
Ali TorkashvandDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
George T FunkenbuschDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Srisatya PusuluriDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
Bo HansenDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
Florian KapellerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Michelle McCallDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
Cynthia A TothDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
Anthony N KuoDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.
Lejla VajzovicDepartment of Ophthalmology, Duke University Eye Center, Durham, NC, 27710, USA.

Funding

Academic/Industry Partnership for Next-Generation Robotically Guided Intraoperative Ophthalmic OCTU01EY037666 · NEI · DUKE UNIVERSITY · PI Anthony Nanlin Kuo, CYNTHIA ANN TOTH · 2025 to 2026
$1.6M
NEI NIH HHS U01 EY037666
6 · The paper itself

Abstract

Intraoperative optical coherence tomography (iOCT) has emerged as a promising modality for real-time three-dimensional image guidance in retinal surgery, enabling visualization of different retinal layers and tool-tissue interactions with micrometer-scale precision. Indirect viewing systems, which employ additional optical elements to increase the surgical field of view (FOV) of the retina, are widely adopted in vitreoretinal procedures. However, the optical design of these indirect viewing systems introduces nonlinear optical distortions that compromise the spatial accuracy required for absolute positioning, such as might be required for robotic end effectors operating in the surgical FOV. In this paper, we present a computationally efficient method to achieve accurate distortion correction between the distorted optical coherence tomography (OCT) image space and the physical surgical workspace through a combination of optical ray tracing and parametric spline fitting. Our approach leverages physics-based ray tracing to characterize the complex optical transformations introduced by the indirect viewing system, then employs numerical spline interpolation to create a fast mapping function suitable for robotic control applications. The spline-based transformation achieves approximately 14 × faster computation than direct commercial software based optical ray tracing. Additionally, we developed a simplified porcine eye model encompassing the cornea through the crystalline lens for use in ray tracing simulations. Validation on

Identifiers

PMID42889903
PMCPMC13671697

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.