Evidence map›Paper›PMID 42889888›Full record

ReviewACS omega2026

PET Imaging of Sphingolipid Signaling: Current Radiotracers, Translational Gaps, and Opportunities in Neurodegeneration and Oncology.

Ryan W Fitzgerald, Paul Josef Myburgh, Kiran K Solingapuram Sai

Abstract readReview
In one paragraph

Review in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ryan W FitzgeraldBiomedical Research Infrastructure Center (BRIC), Winston-Salem State University, Winston-Salem, North Carolina 27110, United States.ORCID https://orcid.org/0000-0003-4592-0356
Paul Josef MyburghTranslational Imaging Program, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID https://orcid.org/0000-0002-6760-607X
Kiran K Solingapuram SaiTranslational Imaging Program, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID https://orcid.org/0000-0002-6442-5169

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sphingolipids regulate membrane organization, cell fate, and immune signaling in both health and disease. Dysregulation of the ceramide, sphingomyelin, and sphingosine-1-phosphate (S1P) pathways contribute to neuroinflammation, neurodegeneration, vascular injury, and cancer, motivating the development of

Identifiers

PMID42889888
PMCPMC13670316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.