Evidence map›Paper›PMID 42889886›Full record

ArticleBiomedical optics express2026

Fabrication of end-coated fibre-optic ultrasound transmitters.

Semyon Bodian, Shaoyan Zhang, Nyma Nassren, Edward Z Zhang, Paul C Beard, Richard J Colchester, Adrien E Desjardins, Erwin J Alles

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Semyon BodianUCL Hawkes Institute, University College London, London, UK.ORCID https://orcid.org/0000-0001-6558-7859
Shaoyan ZhangUCL Hawkes Institute, University College London, London, UK.ORCID https://orcid.org/0000-0002-9563-2873
Nyma NassrenUCL Hawkes Institute, University College London, London, UK.
Edward Z ZhangUCL Hawkes Institute, University College London, London, UK.
Paul C BeardUCL Hawkes Institute, University College London, London, UK.
Richard J ColchesterUCL Hawkes Institute, University College London, London, UK.ORCID https://orcid.org/0000-0001-8657-0546
Adrien E DesjardinsUCL Hawkes Institute, University College London, London, UK.
Erwin J AllesUCL Hawkes Institute, University College London, London, UK.ORCID https://orcid.org/0000-0002-1658-4421

Funding

Wellcome Trust
6 · The paper itself

Abstract

Obliquely emitting fibre-optic optical ultrasound (OpUS) probes show strong potential for guiding minimally invasive procedures, but the imprecise coating methods used to date deposit excess coating along the side of the fibre, which has been suspected to cause imaging artefacts. In this study, we aimed to confirm the source of these artefacts and to introduce an alternative coating method. Optical fibres cleaved at 40° were coated either by conventional dip-coating (DC) or by a new dip-transfer (DT) method, where the curvature of coating droplets allows for accurate alignment of angle-cleaved end-faces. To demonstrate the advantage of DT over DC deposition, fibre-optic ultrasound sources were fabricated using both methods and thoroughly characterised using planar and cylindrical acoustic field scans. Furthermore, a source fabricated with each method was assembled into a fibre-optic OpUS imaging probe and used to image a controlled phantom. DT transmitters generated significantly higher ultrasound pressures than DC transmitters (1.64 ± 0.14 MPa vs 0.53 ± 0.22 MPa, p < 0.05), with comparable mean bandwidths (24.7 ± 1.6 MHz vs 17.3 ± 6.9 MHz) with significantly lower variability. Cylindrical field scans revealed that DC transmitters exhibited strong secondary acoustic lobes (20% of primary beam amplitude), whereas sources fabricated with the DT method did not generate detectable spurious emissions. Imaging trials confirmed that coating of the fibre sides is the primary source of artefacts in obliquely emitting OpUS probes. The DT method effectively eliminates these artefacts while simultaneously enhancing acoustic performance. The higher acoustic performance and the absence of spurious emissions and their associated image artefacts will further advance the quality of OpUS image guidance of minimally invasive interventions. Furthermore, this study reinforces the need for specialised coating methods for obliquely-viewing OpUS probes and highlights the importance the coating coverage in determining image quality.

Identifiers

PMID42889886
PMCPMC13671700

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