Evidence map›Paper›PMID 42889764›Full record

ArticleJPGN reports2026

Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment.

Fabio Rotondo, Antonio Marseglia, Anna Locatelli, Dalila Tedeschi, Marco Gentile, Francesco Perri, Maria Rosa Pastore, Massimo Pettoello Mantovani

Abstract read
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Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Fabio RotondoDepartment of Pediatrics Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.ORCID https://orcid.org/0009-0003-6459-9147
Antonio MarsegliaDepartment of Pediatrics Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.
Anna LocatelliDepartment of Pediatrics Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.
Dalila TedeschiDepartment of Pediatrics University of Foggia Foggia Italy.
Marco GentileDepartmend of Gastroenterology Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.
Francesco PerriDepartmend of Gastroenterology Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.
Maria Rosa PastoreDepartment of Pediatrics Fondazione IRCCS "Casa Sollievo della Sofferenza" San Giovanni Rotondo Italy.
Massimo Pettoello MantovaniDepartment of Pediatrics University of Foggia Foggia Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achalasia is a rare esophageal motility disorder in children, often leading to delayed diagnosis. We report the first two pediatric cases treated with peroral endoscopic myotomy (POEM) at our center, both classified as type II achalasia and complicated by mucosal disease. A 15-year-old girl presented with progressive dysphagia and weight loss, diagnosed with type II achalasia and Candida esophagitis. A 13-year-old boy exhibited similar symptoms with a 27-kg weight loss; histology revealed concurrent eosinophilic esophagitis. Both underwent successful POEM. These cases illustrate the clinical heterogeneity of pediatric achalasia and emphasize the importance of recognizing concomitant mucosal conditions that may delay diagnosis. POEM appears to be a safe and effective, minimally invasive treatment in the pediatric population, even in complex scenarios.

Indexed as

esophageal motility disorderhigh‐resolution manometryminimally invasive endoscopymucosal esophageal disease

Identifiers

PMID42889764
PMCPMC13670152

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.