Evidence map›Paper›PMID 42889749›Full record

ArticleiMeta2026

Domesticated bacterial origin genes regulate homeostasis of the insect gut microbiome and empower adaptation.

Zhenjia Zhang, Yubo Zhang, Kun Zhao, Guangyuan Cheng, Zhihao Lu, Dongju Wang, Yiqun Liu, Jianguo Wu, Liying Wang, Lisheng Zhang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iMeta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhenjia ZhangState Key Laboratory of Agricultural and Forestry Biosecurity, Vector-borne Virus Research Center Fujian Agriculture and Forestry University Fuzhou China.ORCID https://orcid.org/0000-0003-0473-2738
Yubo ZhangState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences Peking University Beijing China.
Kun ZhaoState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences Peking University Beijing China.
Guangyuan ChengState Key Laboratory of Agricultural and Forestry Biosecurity, Vector-borne Virus Research Center Fujian Agriculture and Forestry University Fuzhou China.
Zhihao LuState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences Peking University Beijing China.
Dongju WangThe State Key Laboratory of Membrane Biology Tsinghua University-Peking University Joint Centre for Life Sciences, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University Beijing China.
Yiqun LiuNational Center for Protein Science and Core Facilities at School of Life Sciences Peking University Beijing China.
Jianguo WuState Key Laboratory of Agricultural and Forestry Biosecurity, Vector-borne Virus Research Center Fujian Agriculture and Forestry University Fuzhou China.
Liying WangState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences Peking University Beijing China.
Lisheng ZhangKey Laboratory of Natural Enemy Insects of Ministry of Agriculture and Rural Affairs, State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection, Chinese Academy of Agricultural Sciences Beijing China.
Xinhai YeCollege of Advanced Agriculture Sciences Zhejiang A&F University Hangzhou China.ORCID https://orcid.org/0000-0002-0203-0663
Li YuThe State Key Laboratory of Membrane Biology Tsinghua University-Peking University Joint Centre for Life Sciences, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University Beijing China.
Wei ZhangState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences Peking University Beijing China.
Yi LiState Key Laboratory of Agricultural and Forestry Biosecurity, Vector-borne Virus Research Center Fujian Agriculture and Forestry University Fuzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sap-sucking insects, represented by the globally distributed leafhoppers, have evolved a wide range of adaptive traits and play multiple ecological roles. However, their successful survival strategies in nature remain poorly understood. To explore the adaptive mechanisms of sap-sucking insects, we established a research system using three representative leafhopper species from the same family and found that they have acquired multiple cholesterol-dependent cytolysins (

Indexed as

adaptationcholesterol‐dependent cytolysinfunctional domestication and diversificationgut microbiomeLeafhopper

Identifiers

PMID42889749
PMCPMC13670155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.