Evidence map›Paper›PMID 42889733›Full record

ArticleFrontiers in medicine2026

Case Report: Synchronous double primary male breast cancer and non-small cell lung cancer: diagnostic confirmation and multidisciplinary management.

Ye Zhang, Lei Cao, Yu Zheng, Yang Yang, Xiaoqin Guan, Xiangxin Zheng, Peng Yang, Weiyou Zhu

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ye Zhang *Department of Oncology, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Lei Cao *Department of Oncology, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Yu Zheng *Department of Pathology, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Yang YangDepartment of Oncology, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Xiaoqin GuanDepartment of Thyroid and Breast Surgery, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Xiangxin ZhengDepartment of Thyroid and Breast Surgery, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Peng YangDepartment of Thyroid and Breast Surgery, Jiangsu Province (Suqian) Hospital, Suqian, Jiangsu, China.
Weiyou ZhuDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Male breast cancer (MBC) is rare, accounting for approximately 1% of all breast cancers. When MBC is diagnosed simultaneously with a second primary lung cancer, treatment planning becomes particularly complex because diagnostic certainty, technical resectability, competing treatment windows, and radiotherapy safety must all be considered. Case presentation: We report a 72-year-old man who was synchronously diagnosed with left invasive ductal breast carcinoma and right lower lobe poorly differentiated non-small cell lung cancer (NSCLC). The breast cancer was staged as pT Conclusion: This case illustrates that therapeutic prioritization in synchronous double primary cancers should not be determined solely by TNM stage or chronological order of diagnosis. Instead, treatment decisions should integrate pathological distinction, tumor biology, anatomical treatability, technical resectability, curative potential, competing treatment windows, and short-term clinical threat. In selected patients, simultaneous postmastectomy radiotherapy and definitive lung radiotherapy may be feasible when supported by MDT consensus, dosimetric review, and close toxicity monitoring.

Indexed as

case reportconcurrent thoracic radiotherapydouble primary cancermale breast cancermultidisciplinary teamnon-small cell lung cancertreatment prioritization

Identifiers

PMID42889733
PMCPMC13670921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.