Evidence map›Paper›PMID 42889590›Full record

ArticleACS omega2026

Probiotic-Derived Exopolysaccharides Enhance Mesenchymal Stem Cell-Mediated Fibroblast Repair under Hyperglycemic Conditions.

Mesude Bicer, Mert Akdur, Esra Battal, Fatma Sener, Irem Yilmaz, Özkan Fidan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mesude BicerDepartment of Bioengineering, Faculty of Life and Natural Sciences, Abdullah Gul University, Kayseri 38080, Turkiye.ORCID https://orcid.org/0000-0001-7089-5661
Mert AkdurDepartment of Bioengineering, Faculty of Life and Natural Sciences, Abdullah Gul University, Kayseri 38080, Turkiye.
Esra BattalDepartment of Bioengineering, Faculty of Life and Natural Sciences, Abdullah Gul University, Kayseri 38080, Turkiye.
Fatma SenerDepartment of Bioengineering, Graduate School of Abdullah Gul University, Abdullah Gul University, Kayseri 38080, Turkiye.
Irem YilmazDepartment of Bioengineering, Graduate School of Abdullah Gul University, Abdullah Gul University, Kayseri 38080, Turkiye.
Özkan FidanDepartment of Bioengineering, Faculty of Life and Natural Sciences, Abdullah Gul University, Kayseri 38080, Turkiye.ORCID https://orcid.org/0000-0001-5312-4742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wounds are closely associated with persistent oxidative stress, decreased fibroblast activity, and delayed tissue regeneration under hyperglycemic conditions. These pathological features particularly complicate wound healing and often lead to chronic non-healing wounds. Recently, mesenchymal stem cells (MSCs) and probiotic-derived biomolecules have attracted attention as potential agents to improve tissue repair. In this study, we examined whether the combination of adipose-derived mesenchymal stem cell-conditioned medium (ADMSC-CM) and bacterial exopolysaccharides (EPSs) could improve fibroblast responses under diabetes-like conditions. EPSs were extracted from

Identifiers

PMID42889590
PMCPMC13670295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.