Evidence map›Paper›PMID 42889496›Full record

ReviewFrontiers in pharmacology2026

Targeting glial modulation: molecular mechanisms of Polygonatum in neurological disorders.

Zilong Liu, Yixun Luo, Chuanfeng Zheng, Xiuzhen Long, Yiqi Zhao, Zhiying Pan, Bingyang Xu, Jianfei Sun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zilong LiuChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Yixun LuoChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Chuanfeng ZhengChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Xiuzhen LongChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Yiqi ZhaoChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Zhiying PanChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Bingyang XuChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.
Jianfei SunChemistry and Biochemistry Laboratory, Guizhou Medical University, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological disorders arise from interconnected pathological processes, including oxidative stress, neuroinflammation, mitochondrial dysfunction, impaired proteostasis, synaptic injury and blood brain barrier disruption. Increasing evidence indicates that glial cells are not passive bystanders in these diseases, but central regulators of neuroimmune balance, metabolic support, myelin integrity and tissue repair.

Indexed as

astrocytesmicroglianatural productsneurological diseasesoligodendrocytesPolygonatum

Identifiers

PMID42889496
PMCPMC13669545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.