Evidence map›Paper›PMID 42889491›Full record

ArticleCase reports in otolaryngology2026

Giant Pleomorphic Adenoma of the Parotid Gland: Surgical Management of a Long-Standing Tumor With Facial Deformity and Preservation of Facial Nerve Function.

Francesco Ferragina, Angelo R Sottile, Giuseppe Tarallo, Maria Grazia Ioppolo, Maria Giulia Cristofaro

Abstract read
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Article in Case reports in otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Francesco FerraginaDepartment of Experimental and Clinical Medicine Maxillofacial Surgery Unit Renato Dulbecco Hospital Magna Graecia University of Catanzaro Viale Europa Catanzaro 88100 Italy unicz.it.ORCID https://orcid.org/0000-0002-2522-7768
Angelo R SottileDepartment of Neurosciences Maxillofacial Surgery Operative Unit Reproductive and Odontostomatological Sciences Federico II University of Naples Naples 80131 Italy unina.it.ORCID https://orcid.org/0009-0000-6002-7553
Giuseppe TaralloDepartment of Neurosciences Maxillofacial Surgery Operative Unit Reproductive and Odontostomatological Sciences Federico II University of Naples Naples 80131 Italy unina.it.ORCID https://orcid.org/0009-0006-1979-2599
Maria Grazia IoppoloDepartment of Neurosciences Maxillofacial Surgery Operative Unit Reproductive and Odontostomatological Sciences Federico II University of Naples Naples 80131 Italy unina.it.ORCID https://orcid.org/0009-0003-7655-1685
Maria Giulia CristofaroDepartment of Experimental and Clinical Medicine Maxillofacial Surgery Unit Renato Dulbecco Hospital Magna Graecia University of Catanzaro Viale Europa Catanzaro 88100 Italy unicz.it.ORCID https://orcid.org/0000-0002-6365-8518

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pleomorphic adenoma (PA), the most prevalent benign neoplasm of the parotid gland, typically manifests as a slow-growing, painless mass. In cases where treatment is substantially delayed, the tumor may undergo progressive enlargement, potentially resulting in significant facial deformity. This, in turn, can complicate surgical management. Case Presentation: A 60-year-old female patient exhibited a long-standing right parotid mass that had been gradually increasing in size since 2007, with a notable escalation in dimensions during the year prior to the preliminary assessment. Magnetic resonance imaging in 2021 revealed a well-defined, multilobulated right parotid lesion measuring over 9 cm, and fine-needle aspiration cytology was consistent with PA. Despite the recommendation of surgical excision, the patient initially declined treatment and was subsequently lost to follow-up. In 2025, the patient returned with a parotid mass measuring over 15 cm, accompanied by pronounced facial asymmetry and significant skin stretching. The patient underwent a superficial parotidectomy with complete excision of the lesion, meticulous monitoring of the facial nerve, and preservation of its function. Concurrently, surgical interventions were performed to modify the patient's skin. A subsequent histopathological examination confirmed the presence of PA, devoid of any substantial nuclear atypia or augmented mitotic activity. On Postoperative Day 3, a hematoma developed at the surgical site, necessitating surgical evacuation and hemostatic revision. The ensuing recovery was uneventful, and follow-up at 14 months postoperatively confirmed no recurrence and complete facial nerve function. Conclusions: This case exemplifies the ramifications of protracted untreated growth of a PA, culminating in substantial tumor enlargement and pronounced facial deformity. Notwithstanding the advanced size of the lesion, complete excision was achieved while preserving the function of the facial nerve. In the management of giant parotid tumors, meticulous surgical planning and close postoperative monitoring are paramount.

Indexed as

benign salivary gland tumorfacial asymmetrygiant parotid tumorhead and neck surgerysurgical excision

Identifiers

PMID42889491
PMCPMC13670200

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