ReviewPrzeglad gastroenterologiczny2026
Autopoiesis and organ intelligence: toward a cognitive paradigm in medicine.
Review in Przeglad gastroenterologiczny, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern medicine has been dominated by a neurocentric paradigm that locates cognition exclusively in the brain and treats organs as passive executors of function. Emerging evidence from biology and medicine challenges this view, suggesting that living systems are autopoietic and that organs such as the heart and gut, and the immune system exhibit forms of intrinsic intelligence. This article explores the conceptual foundations and clinical implications of cognitive biology, with particular emphasis on autopoiesis and distributed organ cognition, as a framework for rethinking health, disease, and medical practice. A narrative review was conducted, integrating key contributions from systems theory, cognitive biology, and philosophy of biology with empirical findings from cardiology, gastroenterology, immunology, oncology, and psychoneuroimmunology. Representative case studies and biomedical evidence were selected to illustrate how autopoietic and cognitive principles manifest in clinical contexts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.