Evidence map›Paper›PMID 42889286›Full record

ArticleFrontiers in immunology2026

Single-cell profiling of peripheral immune remodeling in BK polyomavirus-associated nephropathy after kidney transplantation.

Hyunjoo Bae, Eun Jeong Ko, Byung Ha Chung, Eun-Jee Oh

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Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hyunjoo BaeDepartment of Medical Sciences, Graduate School of The Catholic University of Korea, Seoul, Republic of Korea.
Eun Jeong KoDivision of Nephrology, Department of Internal Medicine, The Catholic University of Korea, Bucheon St. Mary's Hospital, Bucheon, Republic of Korea.
Byung Ha ChungDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Eun-Jee OhDepartment of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BK polyomavirus-associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1), BKPyV DNAemia (n = 2), and biopsy-proven BKPyVAN (n = 3). We identified 17 immune cell populations and observed remodeling of both the innate and adaptive compartments. Monocyte subsets differed across clinical states, with CD16

Indexed as

BK VirusKidney DiseasesKidney TransplantationPolyomavirus InfectionsTumor Virus InfectionsFemaleHumansMaleMiddle AgedSingle-Cell AnalysisSingle-Cell Gene Expression AnalysisBK polyomavirus-associated nephropathykidney transplantationperipheral immune remodelingpseudobulk analysisrare immune populationssingle-cell RNA sequencing

Identifiers

PMID42889286
PMCPMC13668843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.