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ArticleFrontiers in pharmacology2026

The selective SIK2/3 inhibitor GLPG3970 exhibits antidepressant-like effects via the hippocampal SIK2-CRTC1-CREB-BDNF pathway in chronic stress models.

Jia-Yi Shen et al.PubMed ↗Full text ↗Publisher ↗

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The selective SIK2/3 inhibitor GLPG3970 exhibits antidepressant-like effects via the hippocampal SIK2-CRTC1-CREB-BDNF pathway in chronic stress models. | OpenQuestion